Hypoxic pulmonary hypertension (HPH) is a devastating disease characterized by progressive vasoconstriction and vascular remodeling.Pirfenidone (PFD) inhibits the progression of HPH, though the molecular mechanisms remain unknown.This study is aimed at determining the role and mechanism of PFD in HPH in human pulmonary artery adventitial fibroblast
Abstract Inducible phenotypic responses to environmental variation are ubiquitous across the tree of life, but it remains an open question whether amphibian chemical defense phenotypes are inducible.Tetrodotoxin (TTX) is a key chemical defense trait in North American and Eurasian newts (Salamandridae).We tested if TTX can be induced by exposing pop
The paper presents the studies on the autolytic transformations in pork and beef 2000 bmw 528i front bumper samples by proteomic methods.The changes in the protein fractions were analyzed by one-dimensional and two- dimensional electrophoresis with the following identification by mass-spectrometric methods.The changes in muscle proteins in the cour
In Brown Planthopper (BPH) has caused losses of rice production in Java due to excessive use of pesticides.This research aims to determine the relationship between crop damages caused by BPH and insecticides use schemes.The pesticide use schemes by farmers were observed in 15 districts on Java which were reported for having severe BPH attacks i.e.B
The free availability of open data provides opportunities to start new businesses and gain business intelligence.However, although data is often used to support decisions and actions, the possibilities offered by modern sensor technologies with connections to cloud-based data collection services are not being effectively capitalized.Data collection